| Name | County | Politics | Elected or Appointed |
| Samuel Crane | Randolph | Republican | 1863 |
| Joseph McWhorter | Roane | Republican | 1864 |
| Joseph McWhorter | Roane | Republican | 1866 |
| Thomas Boggess | Roane | Republican | 1868 |
| 1Edward A. Bennett | Marion | Democrat | 1870- 72 |
| Joseph S. Miller | Cabell | Democrat | 1876 |
| Joseph S. Miller | Cabell | Democrat | 1880 |
| Patrick Fee Duffy | Webster | Democrat | 1884 |
| Patrick Fee Duffy | Webster | Democrat | 1888 |
| Isaac V. Johnson | Barbour | Democrat | 1892 |
| L. M. LaFollette | Taylor | Republican | 1896 |
| Arnold C. Sherr | Mineral | Republican | 1900 |
| Arnold C. Sherr | Mineral | Republican | 1904 |
| John S. Darst | Jackson | Republican | 1908 |
| John S. Darst | Jackson | Republican | 1912 |
| John S. Darst | Jackson | Republican | 1916 |
| John C. Bond | Kanawha | Republican | 1920 |
| John C. Bond | Kanawha | Republican | 1924 |
| 2Sam T. Mallison | Harrison | Republican | 1927- 28 |
| Edgar C. Lawson | Kanawha | Republican | 1928 |
| Edgar B. Sims | Harrison | Democrat | 1932 |
| Edgar B. Sims | Harrison | Democrat | 1936 |
| Edgar B. Sims | Harrison | Democrat | 1940 |
| Edgar B. Sims | Harrison | Democrat | 1944 |
| Edgar B. Sims | Harrison | Democrat | 1948 |
| Edgar B. Sims | Harrison | Democrat | 1952 |
| Edgar B. Sims | Harrison | Democrat | 1956 |
| 3Litz McGuire | Logan | Republican | Appointed June 22, 1960 |
| 4Denzil L. Gainer | Calhoun | Democrat | 1960 |
| 4Denzil L. Gainer | Calhoun | Democrat | 1964 |
| 4Denzil L. Gainer | Calhoun | Democrat | 1968 |
| 5John M. Gates | Raleigh | Democrat | Appointed November 8, 1972 |
| Glen B. Gainer, Jr. | Wood | Democrat | 1976 |
| Glen B. Gainer, Jr. | Wood | Democrat | 1980 |
| Glen B. Gainer, Jr. | Wood | Democrat | 1984 |
| Glen B. Gainer, Jr. | Wood | Democrat | 1988 |
| Glen B. Gainer, III | Wood | Democrat | 1992 |
| Glen B. Gainer, III | Wood | Democrat | 1996 |
| Glen B. Gainer, III | Wood | Democrat | 2000 |
| Glen B. Gainer, III | Wood | Democrat | 2004 |
| Glen B. Gainer, III | Wood | Democrat | 2008 |
| Glen B. Gainer, III | Wood | Democrat | 2012 |
| John B. McCuskey | Kanawha | Republican | 2016 |
1Unopposed in 1872.
2Appointed by Governor, March 18, 1927 to fill vacancy
caused by resignation of John C. Bond, March 15, 1927. Elected in
1928 for unexpired term of John C. Bond, ending March 3,
1929.
3Appointed June 22, 1960, to fill vacancy created by
death of Edgar B. Simms, June 20, 1960.
4Placed on the ballot by the State Democratic Executive
Committee after the death of Edgar B. Simms, June 20, 1960.
5Denzil L. Gainer, died October 31, 1972 but was too
late to place another name on the ballot.